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Cat Number: API1310726603

Upadacitinib

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CAS Number

1310726-60-3

Synonyms

ABT-494
Rinvoq
Upadacitinib anhydrous

Description

Upadacitinib is an oral selective inhibitor of Janus associated kinase 1 (JAK-1) that is used in the therapy of moderate-to-severe rheumatoid arthritis. Upadacitinib has been associated with a low rate of serum enzyme elevations during therapy, but has not been linked to cases of clinically apparent acute liver injury although it may pose a risk for reactivation of hepatitis B in susceptible patients.

Molecular Weight

380.4

Molecular Formula

C17H19F3N6O

SMILES

CCC1CN(CC1C2=CN=C3N2C4=C(NC=C4)N=C3)C(=O)NCC(F)(F)F

Appearance

Powder

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