Cat Number: API58970766

Ubenimex

APIs
CAS Number
58970-76-6
Description
Bestatin is a natural, broad-spectrum, and competitive aminopeptidase inhibitor.
MolecularWeight
308.4
MolecularFormula
C16H24N2O4
SMILEs
CC(C)C[C@@H](C(=O)O)NC(=O)[C@H]([C@@H](CC1=CC=CC=C1)N)O
Appearance
Crystalline or powder
Solubility
Soluble in water
Storage
Desiccate at -20℃
MeltingPoint
233-236℃
BoilingPoint
604.66℃ at 760 mmHg
Density
1.20 g/cm3
RefractiveIndex
1.56
OpticalActivity
α20D -11, c = 1 in 1 M NaOH
IC50
Cytosol aminopeptidase: IC50 = 0.5 nM (bovine); Aminopeptidase N: IC50 = 5 nM (pig); Zinc aminopeptidase: IC50 = 0.28 µM (Plasmodium falciparum FcB1/Columbia); amino peptidase b: IC50 = 1-10 µM
pKValue
pKa: 3.28, pKb: 6.87
FlashPoint
319.5±31.5 ℃
VapourPressure
0.0±1.8 mmHg at 25℃
PreparationUse
a potent aminopeptidase B inhibitor with no carboxypeptidase activity
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