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Cat Number: API13647353

Trilostane

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CAS Number

13647-35-3

Synonyms

Modrenal
Vetoryl
Desopan

Description

Trilostane is a synthetic derivative of androstane with adrenocortical suppressive properties. Trilostane reversibly inhibits 3 beta-hydroxysteroid dehydrogenase delta 5-4 isomerase in the adrenal cortex, resulting in the decreased synthesis of mineralocorticoids and glucocorticoids and the decreased conversion of pregnenolone to progesterone.

Molecular Weight

329.4

Molecular Formula

C20H27NO3

EINECS

237-133-0

SMILES

CC12CCC3C(C1CCC2O)CCC45C3(CC(=C(C4O5)O)C#N)C

Appearance

Yellow-brown Crystalline Solid

Boiling Point

516.5℃ at 760 mmHg