Cat Number: API1197188

Tranexamic acid

APIs
CAS Number
1197-18-8
Description
Tranexamic acid is an antifibrinolytic agent that inhibits plasmin-induced fibrinolysis by binding plasmin.
MolecularWeight
157.21
MolecularFormula
C8H15NO2
SMILEs
NCC1CCC(CC1)C(O)=O
Appearance
Crystalline powder
Solubility
Soluble in water (167 mg/ml), ethanol
Storage
Store at room temperature
MeltingPoint
>300℃ (lit.)
BoilingPoint
~300.2℃ at 760 mmHg
Density
~1.1 g/cm3
OpticalActivity
n20D 1.50
IC50
plasminogen: IC50 = 3.1 µM (human)
pKValue
pKa: 4.65, pKb: 10.27
FlashPoint
135.4±20.4 ℃
VapourPressure
0.0±1.3 mmHg at 25℃
Specification
an inhibitor of fibrinolysis that blocks the interaction of plasmin with fibrin, applicable in the treatment of acute or chronic, localized or systemic primary fiber fibrinolytic hyperthyroidism caused by bleeding
PreparationUse
for injection
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