Synonyms
Trametinib DMSO solvate
TRAMETINIB DIMETHYL SULFOXIDE
Trametinib DMSO
Trametinib (DMSO solvate)
Description
Used for the treatment of patients with unresectable or metastatic melanoma with BRAF V600E or V600K mutations, and who have not received prior BRAF inhibitor treatment. It has a role as an antineoplastic agent and an EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor.
Molecular Formula
C28H29FIN5O5S
SMILES
CC1=C2C(=C(N(C1=O)C)NC3=C(C=C(C=C3)I)F)C(=O)N(C(=O)N2C4=CC=CC(=C4)NC(=O)C)C5CC5.CS(=O)C
Specification
DMF: 2024 Q2