Cat Number: 90604ES

TNFSF13B

Inquiry

Genus

Human

Source

HEK293 cells

Synonyms

BLyS, CD257, TNFSF13B, TNFSF20, TALL-1, BLys, THANK, BAFFB-cell activating factor, ZTNF4

Description

The human BAFF protein, or B-cell activating factor, is a crucial cytokine that plays a significant role in regulating the immune system and promoting B-cell survival and maturation. BAFF is primarily produced by immune cells, including monocytes, macrophages, and dendritic cells. It binds to specific receptors on B cells, allowing their development and preventing apoptosis (cell death). BAFF also influences the production of antibodies and helps regulate the balance of different B-cell subsets.

Molecular Weight

Approximately 18.12 kDa.

Purity

> 90% as determined by SDS-PAGE.

Biological Activity

Human BCMA, His tag immobilized on CM5 chip can bind BAFF, His tag, with an affinity constant of 1.55 x 10-9 M as determined in a SPR assay (Biacore 8K).

Endotoxin

< 0.1 EU per 1μg of the protein by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered concentrated solution in PBS.

Reconstitution

Centrifuge tubes before opening. Dissolve lyophilized protein with PBS. Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.

Note

10, 100, 500μg

HOURS

Daily: 9.30 AM–6.00 PM
Sunday : 9.30 AM–1.00 PM
Holidays: Closed

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