Cat Number: API26921175

Timolol maleate

CAS Number

26921-17-5

Description

Timolol Maleate is a adrenergic receptor antagonist selective for β1-AR. Adrenergic receptors, or adrenoreceptors, are G-protein coupled receptors involved in a variety of sympathetic nervous system processes. Antagonists such as Timolol Maleate that affect the β adrenoreceptors are commonly known as beta blockers that decrease cardiac output.

MolecularWeight

432.492

MolecularFormula

C17H28N4O7S

SMILEs

CC(C)(C)NC[C@@H](COC1=NSN=C1N2CCOCC2)O.C(=C/C(=O)O)\\C(=O)O

Appearance

white to off-white powder

Solubility

Soluble in water (115), alcohol (121), chloroform (140), and DMSO.

Storage

Store at room temperature

MeltingPoint

202-203 ℃(lit.)

BoilingPoint

704.6ºC at 760 mmHg

RefractiveIndex

~1.55

OpticalActivity

[α]25/D -5.4°, c = 4.9 in 1 M HCl(lit.)

IC50

Plasmodium falciparum W2: IC50 = 12.59

FlashPoint

380ºC

VapourPressure

7.7E-21mmHg at 25℃

HOURS

Daily: 9.30 AM–6.00 PM
Sunday : 9.30 AM–1.00 PM
Holidays: Closed

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