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Cat Number: PIPE-0800

Tetrandrine

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CAS Number

518-34-3

Synonyms

D-Tetrandrine
(+)-Tetrandrine
Tetrandrin

Description

Tetrandrine is a natural, bis-benzylisoquinoline alkaloid isolated from the root of the plant Radix stephania tetrandrae. Tetrandrine non-selectively inhibits calcium channel activity and induces G1 blockade of the G1 phase of the cell cycle and apoptosis in various cell types, resulting in immunosuppressive, anti-proliferative and free radical scavenging effects. This agent also increases glucose utilization by enhancing hepatocyte glycogen synthesis, resulting in the lowering of plasma glucose.

Molecular Weight

622.7

Molecular Formula

C38H42N2O6

EINECS

683-095-7

SMILES

CN1CCC2=CC(=C3C=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=C(O3)C(=C(C=C7CCN6C)OC)OC)OC)OC

Appearance

Off-White Solid

Storage

Room temperature