Cat Number: API201341051

Tenofovir Disoproxil

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CAS Number

201341-05-1

Synonyms

PMPA prodrug
Bis(POC)PMPA
9-((R)-2-((Bis(((isopropoxycarbonyl)oxy)methoxy)phosphinyl)methoxy)propyl)adenine

Description

Tenofovir disoproxil is an organic phosphonate that is the disoproxil ester of tenofovir. A prodrug for tenofovir, an HIV-1 reverse transcriptase inhibitor, tenofovir disoproxil is used as the fumaric acid salt in combination therapy for the treatment of HIV infection. It has a role as a prodrug, a HIV-1 reverse transcriptase inhibitor and an antiviral drug.

Molecular Weight

519.4

Molecular Formula

C19H30N5O10P

SMILES

CC(C)OC(=O)OCOP(=O)(COC(C)CN1C=NC2=C(N=CN=C21)N)OCOC(=O)OC(C)C

EINECS

606-442-6

Appearance

White, fine, powder-like crystals

pKa

3.75