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Cat Number: API104987113

Tacrolimus

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CAS Number

104987-11-3

Synonyms

Fujimycin
Prograf
Tsukubaenolide

Description

Tacrolimus (also FK-506 or Fujimycin) is an immunosuppressive drug whose main use is after organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection. It is also used in a topical preparation in the treatment of severe atopic dermatitis, severe refractory uveitis after bone marrow transplants, and the skin condition vitiligo.

Molecular Weight

804

Molecular Formula

C44H69NO12

SMILES

CC1CC(C2C(CC(C(O2)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C(CC(=O)C(C=C(C1)C)CC=C)O)C)C(=CC4CCC(C(C4)OC)O)C)O)C)OC)OC

EINECS

627-021-3

Appearance

White to Off-white Solid

Boiling Point

871.7℃ at 760 mmHg