Syrup Development Services
The pharmaceutical syrup is a nearly saturated aqueous solution of a dissolved medicinal substance or drug usually used for oral administration. It can be said that it is actually used as a vehicle for the drug. Syrups are widely used as the preferred dosage form in the pharmaceutical industry to deliver drugs in a convenient and palatable form for several reasons, including ease of administration, dosage accuracy, and improved patient compliance, especially in pediatric and geriatric populations.
Pharmaceutical syrup development services play a vital role in the formulation and production of liquid medicines. Protheragen-ING offers a one-stop shop for syrup development to meet all your syrup needs, covering a range of projects involving syrup formulation development and dosage form optimization.
Advantages of Syrups
- Syrups are easy to take, especially for people who have difficulty swallowing pills.
- Syrups allow for precise and accurate dosage as they can be measured using a calibrated device such as a spoon or dropper.
- Syrups are often formulated to have a pleasant flavor, which makes them more palatable compared to other forms of medication.
- Syrups in liquid form allow for faster absorption of the medication into the bloodstream compared to solid dosage forms. This allows for faster onset of action and more immediate relief of symptoms.
Common Ingredients in Medicinal Syrups
In addition to water, medicated syrups may contain the following ingredients:
| Ingredient |
Uses |
Common |
| Pharmaceutically active ingredients (APIs) |
The main drug or therapeutic agent that provides the desired effect. |
It can be a single drug or a combination of drugs. |
| Sweetener |
Improve flavor and palatability. |
Sucrose, fructose, sorbitol and artificial sweeteners. |
| Flavorings |
Enhance flavor and mask the bitter or unpleasant taste of the active ingredient. |
Natural or artificial flavors such as fruit extracts, vanillin, or peppermint. |
| Preservative |
Prevent the growth of microorganisms and extend their shelf life. |
Benzoic acid, sorbic acid, sodium benzoate or parabens. |
| Stabilizers and thickeners |
Maintains the uniformity and consistency of the syrup. |
Cellulose derivatives, xanthan gum or astragalus gum. |
Syrup Preparation Process
1. Weighing and measuring: The active ingredients, sweeteners, flavoring agents, and other additives are accurately weighed and measured according to the intended recipe.
2. Mixing: The measured ingredients are mixed in suitable containers or mixing tanks, to ensure an even distribution of the ingredients and to achieve a homogeneous mix.
3. Dissolving: Dissolving the active ingredient and other solid ingredients in a suitable solvent, usually water.
4. Filtration: The syrup mixture is filtered to remove any particulate matter or impurities that may be present.
5. Adding excipients: Once filtration is complete, additional excipients such as preservatives, stabilizers, and thickeners are added and the mixture is thoroughly blended.
6. Final Adjustments: If required, the pH, viscosity, and sweetness of the syrup can be adjusted to meet the desired specifications.
7. Packaging: The final syrup is filled into appropriate containers, such as bottles or plastic containers, and sealed to maintain product integrity.
Application of Pharmaceutical Syrups
Pharmaceutical syrups have a wide range of applications and are used to deliver various types of drugs.
- Analgesics and Antipyretics.
- Cough and Cold Medications.
- Allergy Medications.
- Gastrointestinal Medications.
- Pediatric Medications.
- Vitamins and Supplements.
- Herbal and Natural Remedies.
Contact us today to discuss your syrup formulation development project and take the first step toward bringing your vision to life.
