Suspension Development Services
Pharmaceutical suspensions are an important dosage form in which solid particles are dispersed in a liquid medium. They are widely used in the pharmaceutical industry to deliver water-insoluble or water-insoluble drugs. Suspensions offer several advantages over other dosage forms, making them ideal for drug formulation and delivery.
Protheragen-ING offers a one-stop development service to help optimize API suspension formulations based on the characteristics of the API and the customer's R&D objectives. Whether your drug is to be administered via injectable, ophthalmic, topical, or oral routes, our team of professionals is ready to collaborate. Together, we will customize your drug formulation to not only meet your exact specifications but also to comply with stringent regulatory standards.
Why Choose A Suspension?
- Enhanced Solubility - Drug suspensions can deliver drugs that are less soluble in water.
- Enhanced Stability - Suspensions can enhance the stability of certain drugs by preventing chemical degradation or physical changes such as crystallization.
- Flexible Dosing - Drug suspensions provide dosing flexibility because they can be easily formulated to deliver precise and accurate amounts of drugs.
- Controlled Release - Suspensions can be formulated to provide a controlled release of the drug to achieve a sustained therapeutic effect.
Classification of Suspensions
| Aqueous Suspensions |
These suspensions use water as the liquid medium. They are commonly employed for oral, topical, and parenteral administration. |
| Non-Aqueous Suspensions |
Non-aqueous suspensions use non-aqueous liquids, such as oils or organic solvents, as the dispersion medium. They are often used to deliver lipophilic drugs. |
| Microsuspensions |
Microsuspensions consist of submicron-sized drug particles dispersed in a liquid medium. They offer improved bioavailability and can be used for targeted drug delivery. |
Suspension Development Programs
As a formulation development company, Protheragen-ING can provide development services for a wide range of drug suspensions. Specific development projects will be customized according to your needs and drug properties.
- Oral suspensions.
- Topical suspensions.
- Injectable suspensions.
- Ophthalmic suspensions.
- Nasal suspensions.
- Ear suspensions.
- Parenteral suspensions.
- Highly concentrated suspensions.
- Topical suspensions.
Fig. 1 The preparation process of pharmaceutical suspensions.
Suspension Preparation Method
Protheragen-ING's suspension development services involve a variety of technologies and processes to ensure uniform dispersion and stability of suspensions.
- Wet Milling is a technique that involves reducing the particle size of the drug substance using specialized milling equipment. This helps achieve a uniform particle size distribution and improves the stability of the suspension.
- Homogenization is a process that involves subjecting the drug particles and the liquid medium to high shear forces to break down aggregates and achieve uniform dispersion. This is often done using high-pressure homogenizers or colloid mills.
- Stabilization techniques are employed to prevent particle aggregation and settling in the suspension. Common stabilization methods include the use of surfactants, polymers, and suspending agents.
- Particle Size Characterization is crucial to ensure the desired particle size distribution in the suspension. Techniques such as laser diffraction, microscopy, and sedimentation analysis are commonly used for particle size characterization.
Contact us today to discuss your lotion formulation development project and take the first step toward bringing your vision to life.
