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Cat Number: API341031547

Sunitinib Malate

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CAS Number

341031-54-7

Synonyms

Sutent
SU011248 L-malate salt
PHA-290940AD

Description

An indole and pyrrole derivative that inhibits VEGFR-2 and PDGFR BETA RECEPTOR TYROSINE KINASES. It is used as an antineoplastic agent for the treatment of GASTROINTESTINAL STROMAL TUMORS, and for treatment of advanced or metastatic RENAL CELL CARCINOMA.

Molecular Weight

532.6

Molecular Formula

C26H33FN4O7

SMILES

CCN(CC)CCNC(=O)C1=C(NC(=C1C)C=C2C3=C(C=CC(=C3)F)NC2=O)C.C(C(C(=O)O)O)C(=O)O

EINECS

638-825-9

Appearance

Yellow to Orange Solid

Melting Point

187-191°C