Cat Number: API103628484

Sumatriptan Succinate

CAS Number

103628-48-4

Description

Sumatriptan succinate is a serotonin1 (5-HT1) receptor agonist, which is effective in the acute treatment of migraine headache.

MolecularWeight

341.426

MolecularFormula

C18H27N3O6S

SMILEs

CNS(=O)(=O)CC1=CC2=C(C=C1)NC=C2CCN(C)C.C(CC(=O)O)C(=O)O

Appearance

Powder

Solubility

Soluble in water (83 mg/ml), DMSO (83 mg/ml), and methanol (very slightly). Insoluble in ethanol, and ether.

Storage

Store at 4℃

MeltingPoint

165-166℃

BoilingPoint

497.7ºC at 760 mmHg

Density

1.2±0.1 g/cm³

RefractiveIndex

1.552

IC50

SR-1D: IC50 = 7.3 nM; SR-1B: IC50 = 9.3 nM; SR-1F: IC50 = 17.8 nM; Induce vasoconstriction of human middle meningeal arteries: EC5050 = 89.9 nM

FlashPoint

254.8ºC

VapourPressure

1.24E-17mmHg at 25℃

PreparationUse

A serotonin 5HT1-receptor agonist with anticonvulsant properties, used for migraine relief.

QualitySpecification

USP/EP

Standard

USP/EP

HOURS

Daily: 9.30 AM–6.00 PM
Sunday : 9.30 AM–1.00 PM
Holidays: Closed

INFORMATION

Member of