Cat Number: API3286462

Sulbutiamine

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CAS Number

3286-46-2

Synonyms

Sulbutiamine
bisibutiamine
Bisibuthiamine
Vitaberin

Description

It is highly lipophilic, allowing it to cross the blood-brain barrier more easily than other thiamine derivatives. Although its clinical efficacy is not yet defined, sulbutiamine is used to treat asthenia. While its other uses include improvement of erectile dysfunction and reduction of psycho-behavioural inhibition, sulbutiamine showed evidence of modulatory effect on dopaminergic and glutamatergic cortical transmissions. The chronic administration of the drug has demonstrated to improve long term memory formation in mice.

Molecular Weight

702.89

Molecular Formula

C32H46N8O6S2

SMILES

CC1=NC=C(C(=N1)N)CN(C=O)C(=C(CCOC(=O)C(C)C)SSC(=C(C)N(CC2=CN=C(N=C2N)C)C=O)CCOC(=O)C(C)C)C

EINECS

221-937-3

Appearance

White to Off-White Solid

Melting Point

>136℃