Cat Number: API68373148

Sulbactam acid

APIs
CAS Number
68373-14-8
Description
Sulbactam, a potent β-lactamase inhibitor, serves as a valuable adjunct to enhance the efficacy of other antibiotics. Derived from penicillin, this semi-synthetic compound combats infections caused by β-lactam-resistant bacteria. In human medicine, sulbactam has been utilized alongside ampicillin, cefoperazone, and cefotaxime to treat bacterial infections effectively. The mechanism of action of sulbactam revolves around its ability to impede the activity of β-lactamase enzymes. These enzymes are responsible for the degradation of β-lactam antibiotics, including penicillin and cephalosporins. By obstructing the action of these enzymes, sulbactam enables β-lactam antibiotics to exert their therapeutic effects for extended durations within the body, thereby increasing their overall effectiveness.
MolecularWeight
233.242
MolecularFormula
C8H11NO5S
SMILEs
CC1([C@@H](N2[C@H](S1(=O)=O)CC2=O)C(=O)O)C
Solubility
Soluble in water (47 mg/ml at 25℃), DMSO (47 mg/ml at 25℃), and ethanol (47 mg/ml at 25℃).
Storage
Store at 4℃
MeltingPoint
146-151ºC
BoilingPoint
567.7±50.0 ℃ at 760 mmHg
Density
1.6±0.1 g/cm3
RefractiveIndex
1.605
OpticalActivity
α20D 237.0±4.0, c = 1 in water
FlashPoint
297.1±30.1 ℃
VapourPressure
0.0±3.4 mmHg at 25℃
PreparationUse
A β-lactamase inhibitor. Antidepressant
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