Description
Sulbactam, a potent β-lactamase inhibitor, serves as a valuable adjunct to enhance the efficacy of other antibiotics. Derived from penicillin, this semi-synthetic compound combats infections caused by β-lactam-resistant bacteria. In human medicine, sulbactam has been utilized alongside ampicillin, cefoperazone, and cefotaxime to treat bacterial infections effectively. The mechanism of action of sulbactam revolves around its ability to impede the activity of β-lactamase enzymes. These enzymes are responsible for the degradation of β-lactam antibiotics, including penicillin and cephalosporins. By obstructing the action of these enzymes, sulbactam enables β-lactam antibiotics to exert their therapeutic effects for extended durations within the body, thereby increasing their overall effectiveness.