Cosmetics protect the skin from external aggressors to reduce irritation and redness. They have a soothing or calming effect and make the skin look healthier.
Protheragen-ING recognizes the importance of soothing and calming effects in cosmetics. Our Cosmetic Soothing Efficacy Testing Service aims to provide valuable insights by assessing the effectiveness of various cosmetic products in soothing and comforting the skin.
Protheragen-ING's Testing Services
We tailor testing protocols to specific needs, such as comparative testing, long-term efficacy studies, or sensitivity testing in specific populations.
The testing service will analyze samples for their active ingredients and formulations and conduct in vitro testing to understand their potential soothing properties and identify any potential irritants or allergens.
We use cutting-edge technology to obtain objective measurements to evaluate the soothing benefits of cosmetic products, including assessing skin redness, inflammation, irritation, and hydration levels. Subjective factors, such as participant comfort, are also taken into consideration.
We have a variety of molecular biology techniques at our disposal for in-depth analyses, such as Western blotting, enzyme-linked immunosorbent assay (ELISA), and enzymatic assays.
Once the testing phase is complete, we will provide a comprehensive report summarizing the findings.
Product Evaluation Method
This test method is used to evaluate the soothing and sedative efficacy of test samples at different evaluation intervals, focusing on the product's ability to reduce redness and improve skin smoothness.
Measurements were performed in a dark room. Baseline, one hour, two hours, or four hours following use are among the time intervals.
Melanin and hemoglobin (erythema), the two main pigments that determine skin tone, are measured using equipment based on the absorption and reflection of two particular wavelengths.
Calculating the amount of light absorbed by the skin is possible once the amount of light emitted is known. Calculate the average by taking several readings. It is possible to quantify the calming and energizing effects.
In Vitro Models
Protheragen-ING can provide in vitro testing of different biological models to determine the soothing effect of the test sample. We always select the biological model that best suits your research.
- Primary cells in 2D cultures obtained from all types of donors.
- Dermal or epidermal spheroids, 3D cultured primary cells.
- Human skin explants from young to mature donors.
Test Multiple Possibilities
Protheragen-ING's goal is to test your cosmetic products in the fullest way possible. Our expertise often helps us come up with new testing targets.
In order to study the soothing or calming effects of your product or ingredient, Protheragen-ING may also conduct the following studies.
- Cell metabolism.
- Inflammatory markers.
- Degradation of extracellular matrix.
- Antibacterial and anti-inflammatory peptides.
To find out more about our cosmetic soothing efficacy testing services or to discuss your specific requirements, please contact us. We will respond within 2-4 working days. We look forward to helping you develop and select soothing cosmetics that bring comfort and relief to your skin.
