Synonyms
Sitagliptin (phosphate) MK-0431 sitagliptin phosphate anhydrous
Description
A pyrazine-derived DIPEPTIDYL-PEPTIDASE IV INHIBITOR and HYPOGLYCEMIC AGENT that increases the levels of the INCRETIN hormones GLUCAGON-LIKE PEPTIDE-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). It is used in the treatment of TYPE 2 DIABETES.
Molecular Formula
C16H18F6N5O5P
SMILES
C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)CC(CC3=CC(=C(C=C3F)F)F)N.OP(=O)(O)O
Appearance
White to Off-white Solid
Standard
EP/USP
Facility GMP
Product GMP
Specification
Technical Package
Qualification
ASMF/USMF/NMPA DMF