Description
Simethicone is an orally active defoamer. Simethicone reduces the surface tension of air bubbles in the gastrointestinal tract, causing them to be expelled by vomiting, exhalation or absorption into the bloodstream. Simethicone has potential applications in flatulence and colic.
MolecularFormula
C6H18O4Si3
Solubility
Practically insoluble in water, very slightly soluble or practically insoluble in anhydrous ethanol, practically insoluble in methanol, partly miscible with ethyl acetate, with methylene chloride, with methyl ethyl ketone and with toluene.
BoilingPoint
96.5ºC at 760 mmHg
VapourPressure
5 mm Hg ( 20 ℃)
PreparationUse
a silicon based surfactant that decreases the surface tension of gastrointestinal gas bubbles to facilitate their elimination.
QualitySpecification
EP/USP