Silicone Drug Delivery System Development Services

Protheragen-ING specializes in cutting-edge drug delivery solutions using silicone technology. With our expertise and experience in the field, we offer comprehensive services to support the development and customization of silicone drug delivery systems. Whether you are a pharmaceutical company, a research organization, or a medical device manufacturer, we will help you realize the potential of your silicone drug delivery platform.

Silicones for Drug Delivery

Silicones have emerged as a versatile and promising material for drug delivery applications. These synthetic polymers combine the advantages of biocompatibility, stability, and controlled release to enable precisely controlled release of drugs by modifying their physical and chemical properties, thereby improving drug efficacy and minimizing side effects. Silicones can be formulated into a variety of forms, such as gels, films, coatings, and implants, allowing for precise control of drug release kinetics and improved patient compliance. In addition, their inherent flexibility and ease of manufacture make silicones well-suited for different drug delivery routes, including oral, transdermal, ophthalmic, and implantable systems.

Comprehensive Silicone Drug Delivery Formulations

We can develop many types of silicone drug delivery systems to meet the specific needs and delivery requirements of different drugs. Below are some examples of the types of silicone drug delivery systems we can offer you:

• Transdermal patches and films - We develop silicone patches and films for transdermal drug delivery, enabling controlled and prolonged release of therapeutic drugs through the skin.
• Ophthalmic inserts and implants - Our team specializes in the design of silicone-based ophthalmic drug delivery systems, such as inserts and implants for the treatment of ocular diseases and conditions.
• Implantable devices and scaffolds - We manufacture biocompatible silicone implants and scaffolds that can be used for localized, sustained drug delivery directly at the site of action, promoting tissue regeneration and controlled release.
• Oral drug delivery systems - We design silicone-based oral drug delivery systems, including gastric retention and mucosal adhesion formulations, to improve drug absorption, enhance bioavailability, and target delivery to the gastrointestinal tract.

Fig. 1 Glycerin-silicone membrane for sustained and controlled local delivery of antibacterial and analgesic drugs. (Mazurek P, et al. 2021)

Our Services

We offer a full suite of silicone drug delivery system development services tailored to meet your specific needs.

• Formulation Development

We assist in the formulation of silicone drug carriers, taking into account factors such as drug solubility, release kinetics, stability, and biocompatibility. Our experts use state-of-the-art technology to optimize drug loading, encapsulation efficiency, and release profiles to ensure the desired therapeutic effect is achieved.

• Prototyping

We utilize advanced manufacturing techniques to create prototypes of silicone drug delivery systems. Our prototyping capabilities enable rapid iteration and facilitate efficient design modifications.

• Characterization and Evaluation

We perform comprehensive characterization and evaluation of silicone drug delivery systems to ensure safety, efficacy, and compliance with regulatory standards. Our analytical techniques include physicochemical characterization, drug release studies, stability assessments, and biocompatibility testing.

• Customization and Scale-up

We offer customization services to tailor silicone drug delivery systems to specific drug properties, dosage requirements, and routes of administration. In addition, we assist in the scale-up process, optimizing manufacturing parameters and ensuring a seamless transition from lab-scale to commercial-scale production.

Contact us today to learn how we can help you realize the full potential of silicone-based drug delivery systems.