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Cat Number: 92251ES

SCF-1

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Genus

Human

Source

E.coli

Synonyms

KITLG; FPH2; KL-1; Kitl; MGF; SF; SHEP7; KL

Description

SCF, also known as stem cell factor or kit ligand, is a cytokine that plays a critical role in the survival, proliferation, and differentiation of hematopoietic stem cells and early progenitor cells. SCF is primarily produced by bone marrow stromal cells and functions by binding to the c-kit receptor on the surface of hematopoietic cells. Dysregulation of SCF signaling has been implicated in various types of cancer and hematological disorders.

Molecular Weight

The protein has a predicted MW of 18.45 kDa same as Tris-Bis PAGE result.

Purity

> 95% as determined by SDS-PAGE.

Endotoxin

<1.0 EU per 1μg of the protein by the LAL method.

Formulation

Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.

Reconstitution

Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.

Note

10, 100, 500μg, 1mg

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