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Cat Number: API202805465

Safinamtde Mesytate

CAS Number

202825-46-5

Description

Safinamide is a dopamine reuptake inhibitor by being a highly selective inhibitor of MAO-B (IC50 = 98 nM. Additionally, this compound has a high affinity for Na+ channels (IC50 = 8 μM.

MolecularWeight

398.449

MolecularFormula

C18H23FN2O5S

SMILEs

C[C@H](C(=O)N)NCC1=CC=C(C=C1)OCC2=CC(=CC=C2)F.CS(=O)(=O)O

Appearance

white to tan powder

Solubility

Soluble in water (≥ 15 mg/ml).

Storage

Store at 4℃

MeltingPoint

210° (dec)

BoilingPoint

476.7ºC at 760 mmHg

OpticalActivity

α20D +11.75°±2.25°, c = 1 in 95% acetic acid

IC50

MAO-B: IC50 = 98 nM; Na+ channels: IC50 = 8 µM

FlashPoint

242.1ºC

VapourPressure

2.98E-09mmHg at 25℃

PreparationUse

a highly selective and reversible monoamine oxidase type B (MAO-B) inhibitor that increases neostriatal dopamine concentration.

QualitySpecification

in-house

Standard

in-house

HOURS

Daily: 9.30 AM–6.00 PM
Sunday : 9.30 AM–1.00 PM
Holidays: Closed

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