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Cat Number: API1092939177

Ruxolitinib Phosphate

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CAS Number

1092939-17-7

Synonyms

Jakafi;Jakavi;(R)-3-(4-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile phosphate

Description

Used for the treatment of patients with intermediate or high-risk myelofibrosis, including primary myelofibrosis, post-polycythemia vera myelofibrosis and post-essential thrombocythemia myelofibrosis. It has a role as an antineoplastic agent and an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor.

Molecular Weight

404.4

Molecular Formula

C17H21N6O4P

SMILES

C1CCC(C1)C(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3.OP(=O)(O)O

EINECS

641-390-8

Standard

In-house
Facility GMP

Qualification

DMF/CDE/USMF