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Cat Number: API1211441983

Ribociclib

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CAS Number

1211441-98-3

Synonyms

LEE011
LEE-011
Ribociclib (LEE011)

Description

Ribociclib is a unique cyclin-dependent kinase inhibitor that is used in combination with aromatase inhibitors in the treatment of postmenopausal women with metastatic breast cancer. Ribociclib is associated with a moderate rate of serum aminotransferase elevations during therapy, and to clinically apparent liver injury in a proportion of these.

Molecular Weight

434.5

Molecular Formula

C23H30N8O

SMILES

CN(C)C(=O)C1=CC2=CN=C(N=C2N1C3CCCC3)NC4=NC=C(C=C4)N5CCNCC5

EINECS

807-111-0

Appearance

Yellow Solid

Standard

In-House