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Cat Number: API1809249373

Remdesivir

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CAS Number

1809249-37-3

Synonyms

3QKI37EEHE
GS 5734
GS 5734 [WHO-DD]
GS-5734

Description

A broad-spectrum antiviral prodrug with potent in vitro antiviral activity against a diverse panel of RNA viruses such as Ebola virus, MERS-CoV and SARS-CoV. It is currently in Phase III clinical trials for the treatment of Covid-19 in adults. It has a role as an antiviral drug, a prodrug and an anticoronaviral agent. It is a carboxylic ester, a pyrrolotriazine, a nitrile, a phosphoramidate ester, a C-nucleoside and an aromatic amine. It is functionally related to a GS-441524.

Molecular Weight

602.6

Molecular Formula

C27H35N6O8P

EINECS

852-825-8

SMILES

CCC(CC)COC(=O)C(C)NP(=O)(OCC1C(C(C(O1)(C#N)C2=CC=C3N2N=CN=C3N)O)O)OC4=CC=CC=C4

Appearance

Off-white to yellow (Solid)

Density, g/cm3

1.5±0.1