Description
Rasagiline Mesylate is a selective irreversible MAO-B inhibitor.
MolecularFormula
C13H17NO3S
Solubility
Soluble in DMSO (53 mg/ml at 25℃), methanol, water (53 mg/ml at 25℃), and ethanol (53 mg/ml at 25℃).
OpticalActivity
α20/D +21.5°±6.5°, c = 0.06 in water
IC50
Monoamine oxidase B: IC50 = 4.4 nM (rat); MAO-B: IC50 = 4.4 nM (human); Monoamine oxidase A: IC50 = 0.41 µM (rat); MAO-A: IC50 = 0.41 µM (human)
PreparationUse
Parkinson’s disease