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Cat Number: CHE90319521

R-4-phenyl-2-oxazolidinone

CAS Number

90319-52-1

Synonyms

(R)-(-)-4-Phenyl-2-oxazolidinone
(R)-4-phenyloxazolidin-2-one
(4R)-4-phenyl-1,3-oxazolidin-2-one
(R)-4-PHENYL-2-OXAZOLIDINONE

Description

An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L12) protein, a cholesterol transporter located in the apical membrane of enterocytes.

Molecular Weight

163.17

Molecular Formula

C9H9NO2

SMILES

C1C(NC(=O)O1)C2=CC=CC=C2

Appearance

White to off-white crystalline powder

Boiling Point

407.0±25.0℃ at 760 mmHg

Density, g/cm3

1.195±0.06

Melting Point

129-131℃

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