Synonyms
(R)-(-)-4-Phenyl-2-oxazolidinone
(R)-4-phenyloxazolidin-2-one
(4R)-4-phenyl-1,3-oxazolidin-2-one
(R)-4-PHENYL-2-OXAZOLIDINONE
Description
An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L12) protein, a cholesterol transporter located in the apical membrane of enterocytes.
Molecular Formula
C9H9NO2
SMILES
C1C(NC(=O)O1)C2=CC=CC=C2
Appearance
White to off-white crystalline powder
Boiling Point
407.0±25.0℃ at 760 mmHg
Density, g/cm3
1.195±0.06