Description
Progesterone is a C-21 steroid hormone involved in uterine endothelium activity
MolecularFormula
C21H30O2
SMILEs
CC(=O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C
Solubility
Soluble in alcohol (1:8), chloroform (1:1), ether (1:16), and methanol. Insoluble in water.
MeltingPoint
128-132℃ (lit.)
BoilingPoint
~447.15℃ at 760 mmHg
OpticalActivity
α23D +182, c = 2 in dioxane
IC50
PR: IC50 = 0.2 nM (human); MCR: IC50 = 14 nM (human); AR: IC50 = 37 nM (human); GR: IC50 = 330 nM (human); Estrogen receptor: IC50 = >1 µM (human)
VapourPressure
0.0±1.1 mmHg at 25℃
Specification
a hormone maintaining the female animal pregnancy, and cause a series of physiological changes, such as inhibition of female estrus
PreparationUse
extended release gel