Description
Procaine is a local anesthetic drug of the amino ester group, which acts through multiple targets.
MolecularFormula
C13H20N2O2
SMILEs
CCN(CC)CCOC(=O)C1=CC=C(C=C1)N
Appearance
Crystalline powder
Solubility
Soluble in water (1 g/200ml), ether, benzene, chloroform, ethanol, ethyl ether, alcohol, and water (9.45X10+3 mg/l at 30℃).
BoilingPoint
373.6±22.0 ℃ at 760 mmHg
IC50
Sodium channel protein type III alpha subunit: IC50 = 110 µM (human); Sodium channel protein type VIII alpha subunit: IC50 = 110 µM (human); Sodium channel protein type II alpha subunit: IC50 = 110 µM (human); Sodium channel protein type I alpha subunit: IC50 = 110 µM (human)
pKValue
pKa= 8.05 @ 15 deg C, pKb= 9.24 (Predicted)
VapourPressure
0.0±0.8 mmHg at 25℃
PreparationUse
a local anesthetic used for anesthesia, peripheral nerve block, and spinal nerve block.