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Cat Number: API637581

Pramoxine Hydrochloride

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CAS Number

637-58-1

Synonyms

Pramoxine HCl
Pramocaine hydrochloride
Tronothane

Description

Pramocaine hydrochloride decreases the permeability of the neuronal membrane to sodium ions by reversibly binding to and inhibiting voltage-gated sodium channels. This results in stabilization of the membrane and, thereby inhibiting the ionic fluxes required for membrane depolarization, hence resulting in the failure to initiate a propagated action potential and subsequent conduction blockade.

Molecular Weight

329.9

Molecular Formula

C17H28ClNO3

SMILES

CCCCOC1=CC=C(C=C1)OCCCN2CCOCC2.Cl

EINECS

211-293-1

Appearance

White to Off-white Solid

Melting Point

181-183 ℃