Cat Number: API467426546

Plecanatide

APIs
CAS Number
467426-54-6
Description
Plecanatide, an analogue of uroguanylin, is an orally active guanylate cyclase-C (GC-C) receptor agonist, with an EC50 of 190 nM in T84 cells. Plecanatide can be used for the research of chronic idiopathic constipation, and it also shows anti-inflammatory activity in models of murine colitis.
MolecularWeight
1681.886
MolecularFormula
C65H104N18O26S4
Storage
Store at -20℃
BoilingPoint
2120.0±65.0 ℃ at 760 mmHg
Density
1.5±0.1 g/cm3
RefractiveIndex
1.631
FlashPoint
1235.9±34.3 ℃
VapourPressure
0.0±0.6 mmHg at 25℃
PreparationUse
a laxative used to treat chronic idiopathic constipation and IBS with constipation
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