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Cat Number: API50339

Phenylbutazone

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CAS Number

50-33-9

Description

Phenylbutazone is an inhibitor of Cox.

MolecularWeight

308.38

MolecularFormula

C19H20N2O2

Solubility

Soluble in water (1 mg/ml at 25℃), ethanol (62 mg/ml at 25℃), methanol, DMSO (62 mg/ml at 25℃), and DMF (25 mg/ml).

Storage

Store at room temperature

MeltingPoint

106-108℃ (lit.)

BoilingPoint

~424.9℃ at 760 mmHg

Density

~1.2 g/cm³

RefractiveIndex

1.59

IC50

Cox-1: IC50 = 3 µM (human); Cyclooxygenase-2: IC50 = 3.79 µM (Canis lupus familiaris); PGH synthase : IC50 = 10 µM; Plasmodium falciparum 3D7: IC50 = 10 µM; Plasmodium falciparum D10: IC50 = 12.59 µM

pKValue

pKa: 4.64

PreparationUse

anti-inflammatory drug

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