Cat Number: INT137281233

Pemetrexed

APIs
CAS Number
137281-23-3
Synonyms
Pemetrexed disodium
Alimta
LY231514
Description
Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis.
Molecular Weight
427.42
Molecular Formula
C20H21N5O6
SMILES
C1=CC(=CC=C1CCC2=CNC3=C2C(=O)NC(=N3)N)C(=O)NC(CCC(=O)O)C(=O)O
EINECS
680-625-9
Vapour Pressure
6X10-21 mm Hg at 25 ℃ at 25 ℃ /Estimated/
Application
Pemetrexed Disodium Intermediates
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