Cat Number: INT1013916374

Palbociclib

CAS Number

1013916-37-4

Synonyms

2-Chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one
2-Chloro-8-cyclopentyl-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one
2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7-one
Pyrido[2,3-d]pyrimidin-7(8H)-one, 2-chloro-8-cyclopentyl-5-methyl-

Description

Palbociclib Impurity 63 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.

Molecular Weight

263.72

Molecular Formula

C13H14ClN3O

EINECS

800-066-8

SMILES

CC1=CC(=O)N(C2=NC(=NC=C12)Cl)C3CCCC3

Appearance

Yellow to Dark Yellow Solid

Boiling Point

428.0±34.0 ℃ at 760 mmHg