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Cat Number: API937272792

Pacritinib

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CAS Number

937272-79-2

Synonyms

Pacritinib (SB1518)
SB1518

Description

Pacritinib is a small molecule Janus kinase inhibitor that is used in the treatment of intermediate or high risk, primary or secondary myelofibrosis. Pacritinib is associated with transient and usually mild elevations in serum aminotransferase during therapy but has not been linked instances of clinically apparent acute liver injury.

Molecular Weight

472.6

Molecular Formula

C28H32N4O3

SMILES

C1CCN(C1)CCOC2=C3COCC=CCOCC4=CC(=CC=C4)C5=NC(=NC=C5)NC(=C3)C=C2

EINECS

812-740-9

Boiling Point

711.4±70.0 ℃ at 760 mmHg

Density, g/cm3

1.2±0.1