Cat Number: API33069624S

Paclitaxel (semi-synthetic)

CAS Number

33069-62-4

Description

Paclitaxel is a potent anticancer medication which can promote microtubule (MT) assembly, inhibit MT depolymerization, and change MT dynamics required for mitosis and cell proliferation.

MolecularWeight

853.906

MolecularFormula

C47H51NO14

SMILEs

CC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C5=CC=CC=C5)NC(=O)C6=CC=CC=C6)O)O)OC(=O)C7=CC=CC=C7)(CO4)OC(=O)C)O)C)OC(=O)C

Solubility

Soluble in ethanol (~1.5 mg/ml), DMSO (5 mg/ml), acetonitrile, methanol (50 mg/ml), chloroform, 1:10 DMSO:PBS(pH 7.2) (~0.1 mg/ml), and DMF (~5 mg/ml). Insoluble in water.

MeltingPoint

213 ℃ (dec.)(lit.)

BoilingPoint

957.1±65.0 ℃ at 760 mmHg

Density

1.4±0.1 g/cm³

RefractiveIndex

1.637

FlashPoint

532.6±34.3 ℃

VapourPressure

0.0±0.3 mmHg at 25℃