Cat Number: PIPE-0599

Paclitaxel

APIs
CAS Number
33069-62-4
Synonyms
P88XT4IS4D
Paclitaxel
Taxol
Taxol A
Description
Paclitaxel is a tetracyclic diterpenoid isolated originally from the bark of the Pacific yew tree, Taxus brevifolia. It is a mitotic inhibitor used in cancer chemotherapy. Note that the use of the former generic name 'taxol' is now limited, as Taxol is a registered trade mark. It has a role as a microtubule-stabilising agent, a metabolite, a human metabolite and an antineoplastic agent. It is a tetracyclic diterpenoid and a taxane diterpenoid. It is functionally related to a baccatin III.
Molecular Weight
853.9
Molecular Formula
C47H51NO14
SMILES
CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)C6=CC=CC=C6)O)O)OC(=O)C7=CC=CC=C7)(CO4)OC(=O)C)O)C)OC(=O)C
Appearance
White Solid
Storage
Room temperature
Purity
HPLC≥98%
Boiling Point
957.1℃ at 760 mmHg
Density, g/cm3
1.39
Melting Point
213-216℃
Expiration Time
2years
Applications
ADCs Cytotoxin
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