Package Compatibility and Packaging Sealability Testing

Packaging plays a vital role in maintaining the quality, integrity, and safety of pharmaceuticals, and thorough testing is essential to prevent contamination, degradation, and other potential risks. Ensuring the compatibility and sealing of pharmaceutical products is critical in the pharmaceutical industry.

Protheragen-ING offers comprehensive testing services utilizing industry-recognized methods and state-of-the-art equipment to assess package compatibility and sealing efficacy. With our expertise, you can confidently assess the suitability of packaging materials and safeguard the efficacy of your pharmaceuticals.

The Importance of Our Services

Packaging materials used for pharmaceuticals must be compatible with the drug formulation to ensure stability, efficacy, and safety throughout the shelf life of the drug. Inadequate compatibility can lead to chemical interactions, leaching, or permeation problems that may impair the efficacy of the drug or introduce harmful substances. Similarly, the sealing integrity of the package is critical to prevent the entry of moisture, oxygen, light, or other contaminants that may degrade the drug or compromise its sterility. By conducting thorough compatibility and seal testing, drug manufacturers can identify potential risks and take the necessary steps to mitigate them, ensuring the reliability and safety of their products.

Our Packaging Compatibility Testing Services

We offer a comprehensive pharmaceutical packaging compatibility testing program designed to evaluate the interaction of your drug formulation with various packaging materials. Our experienced team utilizes industry-recognized methods such as stability studies, extractable and leachable testing, and accelerated aging studies to evaluate the compatibility of your drug with different packaging types. We consider factors such as chemical compatibility, permeation, and absorption to identify any potential risks and advise on suitable packaging solutions. Our testing program covers a wide range of pharmaceutical products, including solid dosage forms, liquid formulations, injectable products, and more.

Common packaging types we assess include:

• Blister Packs - We assess the compatibility of your drug formulation with blister packaging materials, ensuring proper barrier properties, stability, and protection against light and moisture.
• Bottles and Containers - Our testing evaluates the interaction of your medication with a variety of bottle/container materials, including glass, plastic, or metal, to ensure compatibility, chemical stability, and leachability.
• Ampoules and Vials - We check the compatibility of your drug with ampoules and vials, evaluating factors such as risk of glass delamination, container closure integrity, and extractable and leachable characteristics.
• Prefilled Syringes - Our testing program includes evaluating the compatibility of your drug with prefilled syringes, taking into account factors such as rubber stopper compatibility, extractables, leachables, and syringe functionality.

Our Packaging Sealability Testing Services

Our package seal testing services are designed to ensure that pharmaceutical packaging maintains an effective barrier against external contaminants and preserves product integrity. We utilize advanced testing methods to assess the integrity and quality of package seals. We can test different types of package seals, such as induction seals, blister pack seals, screw caps, and snap caps.

Applications of our seal testing program include:

• Blister packs.
• Bottles and containers.
• Ampoules and vials.
• Pre-filled syringes.

Contact us today to learn more about our packaging compatibility and package seal testing services and how we can help you meet regulatory requirements and maintain the highest quality standards.