Cat Number: PIPE-0596

Omacetaxine;Homoharringtonine

APIs
CAS Number
26833-87-4
Synonyms
homoharringtonine
Omacetaxine mepesuccinate
Myelostat
Ceflatonin
Description
Omacetaxine mepesuccinate is a cephalotaxine-derived alkaloid ester obtained from Cephalotaxus harringtonia; used for the treatment of chronic or accelerated phase chronic myeloid leukaemia. It has a role as an antineoplastic agent, a protein synthesis inhibitor, an apoptosis inducer and an anticoronaviral agent. It is an alkaloid ester, a tertiary alcohol, an organic heteropentacyclic compound and an enol ether. It is functionally related to a cephalotaxine.
Molecular Weight
545.6
Molecular Formula
C29H39NO9
EINECS
636-662-8
SMILES
CC(C)(CCCC(CC(=O)OC)(C(=O)OC1C2C3=CC4=C(C=C3CCN5C2(CCC5)C=C1OC)OCO4)O)O
Appearance
Cryst.
Storage
Room temperature
Purity
0.98
Density, g/cm3
1.33
Expiration Time
2years
Applications
Anti-leukemic
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