Cat Number: PIPE-0596

Omacetaxine;Homoharringtonine

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CAS Number

26833-87-4

Synonyms

homoharringtonine Omacetaxine mepesuccinate Myelostat Ceflatonin

Description

Omacetaxine mepesuccinate is a cephalotaxine-derived alkaloid ester obtained from Cephalotaxus harringtonia; used for the treatment of chronic or accelerated phase chronic myeloid leukaemia. It has a role as an antineoplastic agent, a protein synthesis inhibitor, an apoptosis inducer and an anticoronaviral agent. It is an alkaloid ester, a tertiary alcohol, an organic heteropentacyclic compound and an enol ether. It is functionally related to a cephalotaxine.

Molecular Weight

545.6

Molecular Formula

C29H39NO9

EINECS

636-662-8

SMILES

CC(C)(CCCC(CC(=O)OC)(C(=O)OC1C2C3=CC4=C(C=C3CCN5C2(CCC5)C=C1OC)OCO4)O)O

Appearance

Cryst.

Storage

Room temperature