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Cat Number: INT763114267

Olapali Intermediate 3

CAS Number

763114-26-7

Synonyms

2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic acid
2-fluoro-5-[(4-oxo-3,4-dihydrophthalazin-1-yl)methyl]benzoic acid
2-Fluoro-5-[(4-oxo-3H-phthalazin-1-yl)methyl]benzoic acid
Benzoic acid, 5-[(3,4-dihydro-4-oxo-1-phthalazinyl)methyl]-2-fluoro-

Description

2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic acid is an impurity of olaparib, which selectively binds and inhibits PARP, inhibiting PARP-mediated repair of single-strand DNA breaks.

Molecular Weight

298.27

Molecular Formula

C16H11FN2O3

SMILES

C1=CC=C2C(=C1)C(=NNC2=O)CC3=CC(=C(C=C3)F)C(=O)O

EINECS

800-110-6

Density, g/cm3

1.4±0.1

Application

Olaparib Intermediates