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Cat Number: API656247186

Nintedanib Esylate

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CAS Number

656247-18-6

Synonyms

BIBF 1120 esylate
Nintedanib ethanesulfonate
Nintedanib Ethanesulfonate Salt

Description

A kinase inhibitor used for the treatment of idiopathic pulmonary fibrosis and cancer. It has a role as an angiogenesis inhibitor, an antineoplastic agent, a fibroblast growth factor receptor antagonist, a tyrosine kinase inhibitor and a vascular endothelial growth factor receptor antagonist.

Molecular Weight

649.8

Molecular Formula

C33H39N5O7S

SMILES

CCS(=O)(=O)O.CN1CCN(CC1)CC(=O)N(C)C2=CC=C(C=C2)N=C(C3=CC=CC=C3)C4=C(NC5=C4C=CC(=C5)C(=O)OC)O

Appearance

Yellow solid powder

Melting Point

>233℃ (dec.)

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