Cat Number: API656247186

Nintedanib Esylate

APIs
CAS Number
656247-18-6
Synonyms
BIBF 1120 esylate Nintedanib ethanesulfonate Nintedanib Ethanesulfonate Salt
Description
A kinase inhibitor used for the treatment of idiopathic pulmonary fibrosis and cancer. It has a role as an angiogenesis inhibitor, an antineoplastic agent, a fibroblast growth factor receptor antagonist, a tyrosine kinase inhibitor and a vascular endothelial growth factor receptor antagonist.
Molecular Weight
649.8
Molecular Formula
C33H39N5O7S
SMILES
CCS(=O)(=O)O.CN1CCN(CC1)CC(=O)N(C)C2=CC=C(C=C2)N=C(C3=CC=CC=C3)C4=C(NC5=C4C=CC(=C5)C(=O)OC)O
Appearance
Yellow solid powder
Melting Point
>233℃ (dec.)
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