Description
Netupitant is a highly potent and selective, orally active neurokinin-1 receptor antagonist with Ki of 0.95 nM.
MolecularFormula
C30H32F6N4O
SMILEs
CC1=CC=CC=C1C2=CC(=NC=C2N(C)C(=O)C(C)(C)C3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F)N4CCN(CC4)C
BoilingPoint
597.4±50.0 ℃ at 760 mmHg
VapourPressure
0.0±1.7 mmHg at 25℃
PreparationUse
an antiemetic agent used in combination with palonosetron to prevent acute and delayed vomiting and nausea caused by chemotherapy.