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Cat Number: API915942222

Neratinib Maleate

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CAS Number

915942-22-2

Synonyms

hki-272 maleate
Nerlynx
Neratinib maleate [MI]

Description

Neratinib Maleate is the maleate salt form of neratinib, an orally available, quinazoline-based, irreversible inhibitor of both the receptor tyrosine kinases (RTKs) human epidermal growth factor receptor 2 (HER2; ERBB2) and human epidermal growth factor receptor (EGFR), with potential antineoplastic activity.

Molecular Weight

673.1

Molecular Formula

C34H33ClN6O7

SMILES

CCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)OCC4=CC=CC=N4)Cl)C#N)NC(=O)C=CCN(C)C.C(=CC(=O)O)C(=O)O

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