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Cat Number: API22204531

Naproxen

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CAS Number

22204-53-1

Description

Naproxen is a Cox-1 and Cox-2 inhibitor.

MolecularWeight

230.26

MolecularFormula

C14H14O3

Solubility

Soluble in water (>3 mg/mL at 25℃), PBS pH 7.2, SOL., ethanol, DMSO, DMF (100 mg/mL), chloroform, dichloromethane, ether, ethyl acetate, methanol, and THF.

Storage

Store at room temperature

MeltingPoint

152-154℃ (lit.)

BoilingPoint

~403.9℃ at 760 mmHg

Density

~1.2 g/cm³

RefractiveIndex

1.61

OpticalActivity

α20D 66, c = 1 in chloroform

IC50

recombinant COX-1: IC50 = 0.6-4.8 µM (human); recombinant COX-2: IC50 = 2.0-28.4 µM (human)

pKValue

pKa: 4.85

PreparationUse

nonsteroidal anti-inflammatory dug (NSAID)

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