Cat Number: INT220000873

N-Methyl-4-chloropyridine-2-carboxamide

CAS Number

220000-87-3

Synonyms

4-Chloro-N-methylpicolinamide
4-Chloro-N-methylpyridine-2-carboxamide
N-Methyl-4-chloropyridine-2-carboxamide
4-Chloro-N-methyl-2-pyridinecarboxamide

Description

N-Methyl-4-chloropyridine-2-carboxamide is an impurity of Sorafenib, which is a kinase inhibitor drug used for the treatment of primary kidney cancer (advanced renal cell carcinoma), advanced primary liver cancer (hepatocellular carcinoma), FLT3-ITD positive AML and radioactive iodine resistant advanced thyroid carcinoma.

Molecular Weight

170.59

Molecular Formula

C7H7ClN2O

SMILES

CNC(=O)C1=NC=CC(=C1)Cl

Appearance

Off-white to light yellow low-melting solid

Boiling Point

317.8±27.0 ℃ (Predicted)

Density, g/cm3

1.264±0.06