Cat Number: API13614987

Minocycline Hydrochloride

APIs
CAS Number
13614-98-7
Description
Minocycline, Hydrochloride is a broad-spectrum tetracycline antibiotic that also acts as PARP inhibitor.
MolecularWeight
493.94
MolecularFormula
C23H27N3O7•HCl
SMILEs
CN(C)[C@H]1[C@@H]2C[C@@H]3CC4=C(C=CC(=C4C(=C3C(=O)[C@@]2(C(=O)/C(=C(/N)\\O)/C1=O)O)O)O)N(C)C.Cl
Solubility
Soluble in DMSO (7 mg/ml), water (50 mg/ml), methanol, and aqueous solutions of alkali hydroxides and carbonates.
Storage
Store at 4℃
MeltingPoint
193-226℃
BoilingPoint
659.4ºC at 760mmHg
RefractiveIndex
~1.72
OpticalActivity
α20D -175, c = 0.5 in 0.1ml/L HCl
IC50
Plasmodium falciparum W2: IC50 = 794.33 nM
pKValue
pKa: 4.5, pKb: 11.06
FlashPoint
352.6ºC
VapourPressure
6.33E-28mmHg at 25℃
Specification
Second generation tetracycline antibiotic. Antibacterial and antiinflammatory
PreparationUse
ER tablets
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