Cat Number: INT73573883

Mevastatin/Compactin

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CAS Number

73573-88-3

Synonyms

Compactin
EC 700-442-0
Mevastatin
ML-236B

Description

A hydroxymethylglutaryl-CoA reductase inhibitor (statin) isolated from Penicillium citrinum and from Penicillium brevicompactum, its clinical use as a lipid-regulating drug ceased following reports of toxicity in animals. It has a role as a fungal metabolite, an EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor, an antifungal agent, a Penicillium metabolite and an apoptosis inducer.

Molecular Weight

390.5

Molecular Formula

C23H34O5

SMILES

CCC(C)C(=O)OC1CCC=C2C1C(C(C=C2)C)CCC3CC(CC(=O)O3)O

EINECS

700-442-0

Appearance

White to Off-White Solid

Boiling Point

555.0±50.0 ℃ (Predicted)