Cat Number: API96036032

Meropenem

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CAS Number

96036-03-2

Description

Meropenem is an antibiotic of the carbapenem subclass that has a high affinity for cell wall-synthesizing enzymes.

MolecularWeight

383.46

MolecularFormula

C17H25N3O5S

Appearance

Crystalline powder

Solubility

Soluble in water (8 mg/ml at 25℃), 5% monobasic potassium phosphate solution, ethanol

Storage

Store at 4℃

MeltingPoint

325.85℃

BoilingPoint

~627.4℃ at 760 mmHg

Density

~1.4 g/cm³

RefractiveIndex

1.64

OpticalActivity

α20D -19±2, c = 0.44 in water

IC50

Displacement of [14C]benzylpenicillin : IC50 = 3.3 ng/ml (Pseudomonas aeruginosa ATCC 15692); Binding of bocillin FL to PBP4 : IC50 = 8 ng/ml (Pseudomonas aeruginosa PAO1 membranes); Binding of bocillin FL to PBP2 : IC50 = 8 ng/ml (Escherichia coli MC4100 membranes)

pKValue

pKa: 4.27, pKb: 8.31

PreparationUse

Antibiotic

HOURS

Daily: 9.30 AM–6.00 PM
Sunday : 9.30 AM–1.00 PM
Holidays: Closed

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