Melting Point Test

What Is the Melting Point?

Melting point refers to the temperature at which a substance changes from solid to liquid.

At the melting point, the solid and liquid states are in equilibrium with each other. The melting point of a substance depends on pressure and is usually specified at standard pressure, usually 1 atmosphere.

When a solid is heated, its temperature will continue to increase until it reaches its melting point, and the accumulated heat will convert the solid into a liquid, while the temperature remains constant.

Why Measure the Melting Point of a Drug?

• Quality Control - The melting point of a drug is measured to check its purity and quality. Melting point evaluation is one of the important techniques for testing the purity of pharmaceutical compounds. Melting point testing is an important item in pharmaceutical quality inspection standards.
• Performance Prediction - There is a certain relationship between the melting point of a drug and its efficacy. The melting point is related to the chemical stability of the compound, which affects the distribution and efficacy of the drug in the body. The melting point can also be used to model other important physicochemical properties, such as vapour pressure and water solubility. These properties are of great significance for the design, screening and optimization of drugs.

Services at Protheragen-ING

Sample Processing

Once we receive the sample we proceed to the careful preparation (commonly involves grinding the compound into a fine powder with uniform particles) of your drug sample. Ensuring its purity and quality is essential for accurate results.

Melting Point Analysis

Our expert team employs melting point apparatuses to precisely determine the melting point of the drug substance. This apparatus uses controlled heating to monitor temperature changes and detect the exact point at which the substance transitions from a solid to a liquid.

Because there are errors that involve visual observation, we performed a minimum of three measurements for each sample and subsequently averaged the results to ensure the utmost accuracy.

Reporting

We provide a comprehensive report that not only includes the final measurement value but also data obtained at each measurement.

Follow-up Support

After delivering the report, our team remains available to address any questions or provide additional support. We are committed to ensuring that clients have all the necessary information and guidance to use data effectively in pharmaceutical research and development.

Our commitment to precision and accuracy ensures reliable data. If you have any questions or need further assistance please contact us and we will respond within 2-4 working days.