Cat Number: API71589

medroxyprogesterone acetate

APIs
CAS Number
71-58-9
Description
Medroxyprogesterone 17-Acetate is a synthetic progesterone receptor agonist.
MolecularWeight
386.52
MolecularFormula
C24H34O4
Appearance
Crystalline powder
Solubility
Soluble in DMF, ethanol (12 mg/ml at 25℃), methanol (sparingly), DMSO (12 mg/ml at 25℃), water
Storage
Store at -20℃
MeltingPoint
206-207℃ (lit.)
BoilingPoint
~496.4℃ at 760 mmH
Density
~1.1 g/cm3
RefractiveIndex
1.54
OpticalActivity
α20D +47, c = 1 in dioxane
IC50
Progesterone receptor: IC50 = 2.25 nM (bovine); AR: IC50 = 6.1 nM (human); GR: IC50 = 10 nM (human); Estrogen receptor: IC50 = 0.92 µM (human); MCR: IC50 = 1.20 µM (human)
PreparationUse
secondary amenorrhea, abnormal uterine bleeding, pain from endometriosis, endometrial and renal carcinomas, paraphilia in males
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